OHSU scientist successfully modifies DNA in human embryos, report says

OHSU scientist successfully modifies DNA in human embryos, report says

In December 2015, a group of worldwide scientists and ethicists, including some from China, assembled by the US National Academy of Sciences said it would be irresponsible to use DNA editing tools to alter the genomes of human embryos, eggs, or sperm until safety, ethical and legal issues were resolved.

Researchers at the Oregon Health and Science University (OHSU) in Portland have carried out the first known attempt at creating genetically modified human embryos in the United States.

Shoukhrat Mitalipov of Oregon Health & Science University targeted a gene associated with a human disease, surpassing work done in China, the report said. The fear is that it can lead to manipulating the human genome at will-not only to correct genetic defects, but to enhance certain human characteristics, such as athleticism and intelligence, and remove those viewed as undesirable. It is thought to be the first such work in the US; previous experiments like this have been reported from China. Many are drooling to engage in eugenic genetic enhancements. CRISPR is a very precise gene-editing tool, but it can sometimes lead to editing errors.

North Korea could launch nuclear-capable missile by next year
United States gave China a draft resolution weeks ago to impose greater sanctions on North Korea for its July 4 missile launch. Defense officials suggested that another ballistic missile test could come within a matter of days, according to Reuters.

Chinese researchers have also modified human embryos with CRISPR.

But in March this year, that academy and the American Medical Academy said in a new report that recent advances in the field "opened up a realistic possibility that deserves serious consideration".

But many are opposed to these types of experiments over concerns it could be used to create "designer babies". Or you could have the National Academy of Sciences work with industry and Congress to lay out a review committee and permit funding. "I don't think it's the start of clinical trials yet, but it does take it further than anyone has before", said a scientist familiar with the project.

Eight people found dead in semi truck trailer
In 2003, 19 immigrants were killed after their smugglers abandoned them in the back of a trailer in Victoria, Texas . US Immigration and Customs Enforcement (ICE) officials defended the use of tough methods to fight human smuggling.

Engineered humans are still far away into the future. If such a genetically modified child were born, they would pass on the edited changes in their DNA to subsequent generations.

And earlier this year in the USA, the National Academy of Sciences and National Academy of Medicine said in a report that altering the genes of embryos might be OK if done under strict criteria and aimed at preventing serious disease.

"This was purely laboratory-based work that is incredibly valuable for helping us understand how one might make these germline changes in a way that is precise and safe". Technology Review could not determine which disease genes had been chosen for editing. Stanford University law professor and bioethicist Hank Greely tweeted that "the key point" is that no one has tried to implant any edited embryos.

The Cleveland Cavaliers should pass on signing Derrick Rose
Rose averaged 18 points, 3.8 rebounds and 4.4 assists on 47 percent shooting in 64 games for the New York Knicks last season. He would be an immediate upgrade over Jose Calderon and would be the backup point guard behind Kyrie Irving .

Related Articles